Protein Information

Name Stimulator of Fe Transport
Synonyms E2(17)KB 1; E2(17)KB1; SFT; UBC4/5; UBCH 5; UBCH5; UBCH5A; UBE2D1…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
10092211 Gutierrez JA, Inman RS, Akompong T, Yu J, Wessling-Resnick M: Metabolic depletion inhibits the uptake of nontransferrin-bound iron by K562 cells. J Cell Physiol. 1998 Dec;177(4):585-92.

Incubation with 1 microM rotenone, 10 microM antimycin, or 0.5 mM 2,4-dinitrophenol effectively reduced ATP levels by approximately 50%.
These features possibly reflect properties of the transport mechanism associated with a recently identified K562 cell transport protein, called SFT for "Stimulator of Fe Transport," since exogenous expression of its activity is also affected by ATP depletion.
1(0,0,0,1) Details