| Name | Nerve growth factor |
|---|---|
| Synonyms | Beta NGF; Beta nerve growth factor; Beta nerve growth factor precursor; HSAN 5; HSAN5; NGF; NGFB; Nerve growth factor… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16887804 | Jiang Q, Yan Z, Feng J: Neurotrophic factors stabilize microtubules and protect against rotenone toxicity on dopaminergic neurons. J Biol Chem. 2006 Sep 29;281(39):29391-400. Epub 2006 Aug 3. Here we show that nerve growth factor (NGF) significantly reduced rotenone toxicity on TH (+) neurons in midbrain neuronal cultures. |
81(1,1,1,1) | Details |
| 17686240 | Wang L, Cao XB, Wang JM, Qu RS, Xu L, Qiao X, Sun SG: [Proteolytic stress induced by environmental toxins in dopaminergic neurons: an experimental study]. Zhonghua Yi Xue Za Zhi. 2007 May 8;87(17):1190-4. METHODS: Nerve growth factor-treated-rat adrenal pheochromocytoma cells of the line PC12 were co-incubated with (6-OHDA), 1-methyl-4-phenylpyridinium ion (MPP (+)), and rotenone for 24 hours. |
6(0,0,1,1) | Details |
| 10797558 | Lamensdorf I, Eisenhofer G, Harvey-White J, Hayakawa Y, Kirk K, Kopin IJ: Metabolic stress in PC12 cells induces the formation of the endogenous dopaminergic neurotoxin, 3,4-dihydroxyphenylacetaldehyde. J Neurosci Res. 2000 May 15;60(4):552-8. Nerve growth factor-induced differentiation of PC12 cells markedly potentiated DOPAL and DOPET accumulation in response to metabolic stress. |
1(0,0,0,1) | Details |
| 17029596 | Hirata Y, Meguro T, Kiuchi K: Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis. J Neurochem. 2006 Oct;99(2):416-25. Both rotenone and are possible neurotoxins for a wide variety of cell and neuronal types including dopaminergic neurons and induce apoptosis in various cells. |
1(0,0,0,1) | Details |
| 12588799 | Darios F, Corti O, Lucking CB, Hampe C, Muriel MP, Abbas N, Gu WJ, Hirsch EC, Rooney T, Ruberg M, Brice A: Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum Mol Genet. 2003 Mar 1;12(5):517-26. In this cell line, neuronally differentiated by nerve growth factor, Parkin overproduction protected against cell death mediated by but not by a variety of other cell death inducers (H (2) O (2), rotenone, 6-OHDA, tunicamycin, 2-mercaptoethanol and staurosporine). |
0(0,0,0,0) | Details |
| 14766796 | Lapointe N, St-Hilaire M, Martinoli MG, Blanchet J, Gould P, Rouillard C, Cicchetti F: Rotenone induces non-specific central nervous system and systemic toxicity. FASEB J. 2004 Apr;18(6):717-9. Epub 2004 Feb 6. |
0(0,0,0,0) | Details |