| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17382198 | Millar TM, Phan V, Tibbles LA: ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment. Free Radic Biol Med. 2007 Apr 15;42(8):1165-77. Epub 2007 Jan 13. During hypoxia, an increase in cytoplasmic ROS and glutathione S-transferase activity occurred, suggesting changes in intracellular redox state, mimicked with rotenone or FCCP but inhibited by antimycin A. |
31(0,1,1,1) | Details |
| 12151355 | Tanaka T, Kohno H, Sakata K, Yamada Y, Hirose Y, Sugie S, Mori H: Modifying effects of dietary and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Carcinogenesis. 2002 Aug;23(8):1361-7. In pilot studies, gavage with and rotenone elevated the phase II enzymes glutathione S-transferase (GST) and quinone reductase (QR), in the liver and tongue. |
6(0,0,1,1) | Details |
| 11604990 | Yoshitani SI, Tanaka T, Kohno H, Takashima S: Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary and rotenone. Int J Oncol. 2001 Nov;19(5):929-39. Gavage with and rotenone significantly elevated phase II enzymes, glutathione S-transferase (GST) and quinone reductase (QR), in the liver and colon. |
6(0,0,1,1) | Details |
| 19269317 | Goto S, Kawakatsu M, Izumi S, Urata Y, Kageyama K, Ihara Y, Koji T, Kondo T: Glutathione S-transferase pi localizes in mitochondria and protects against oxidative stress. Free Radic Biol Med. 2009 May 15;46(10):1392-403. Epub 2009 Mar 6. Glutathione S-transferases (GSTs) are multifunctional enzymes involved in the protection of cellular components against anti-cancer drugs or peroxidative stress. Chemicals generating reactive species, such as rotenone and antimycin A, decreased cell viability and reduced mitochondrial membrane potential. |
1(0,0,0,1) | Details |
| 17657281 | Panee J, Liu W, Nakamura K, Berry MJ: The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of supplementation. Int J Biol Sci. 2007 Jul 13;3(5):335-41. Complex I blockade upregulated the mRNA levels of glutamylcysteine synthetase heavy and light chains, glutathione-S-transferases omega1 and alpha 2, hemoxygenase 1, thioredoxin reductase 1, and selenoprotein H. |
1(0,0,0,1) | Details |