Protein Information

Name ceruloplasmin
Synonyms CP; CP protein; Ceruloplasmin; Ceruloplasmin precursor; Ferroxidase; ceruloplasmin (ferroxidase); CP; CP proteins…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
18804145 Kaneko K, Hineno A, Yoshida K, Ikeda S: Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice. Neurosci Lett. 2008 Nov 28;446(1):56-8. Epub 2008 Sep 11.
 7(0,0,1,2) Details
19019832 Tapryal N, Mukhopadhyay C, Das D, Fox PL, Mukhopadhyay CK: Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases. J Biol Chem. 2009 Jan 16;284(3):1873-83. Epub 2008 Nov 18.

In this study we demonstrated that Cp expression is decreased by an mRNA decay mechanism in response to extracellular (H2O2) or intracellular oxidative stress (by mitochondrial chain blockers rotenone or antimycin A) in both hepatic and astroglial cells.		 2(0,0,0,2) Details