| 19576886 |
Matsuo J, Oku H, Kanbara Y, Kobayashi T, Sugiyama T, Ikeda T: Involvement of NADPH oxidase and protein kinase C in endothelin-1-induced superoxide production in retinal microvessels. Exp Eye Res. 2009 Nov;89(5):693-9. Epub 2009 Jul 2.
The receptor mechanisms were determined by BQ-123 and BQ-788, receptor antagonists for ET (A) and ET (B) receptors, respectively, and also by IRL-1620, a selective agonist for ET (B) receptors.
In addition, the changes induced by adding apocynin (10 microM), myr-PKC (1.0 microM), allopurinol (100 microM), rotenone (10 microM), or L-NAME (100 microM) with ET-1 were evaluated. |
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