Protein Information

Name tripeptidyl peptidase II
Synonyms TPP 2; Tripeptidyl aminopeptidase; TPP II; TPP2; Tripeptidyl peptidase II; Tripeptidyl peptidase 2; Tripeptidyl peptidase IIs; Tripeptidyl peptidase 2s

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
19747897 Preta G, de Klark R, Glas R: A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses. Biochem Biophys Res Commun. 2009 Nov 27;389(4):575-9. Epub 2009 Sep 10.

Further, this required cellular production of ROS; treatment with either N-acetyl-Cysteine (anti-oxidant) or Rotenone (inhibitor of mitochondrial respiration) inhibited nuclear accumulation of TPPII.
2(0,0,0,2) Details