| Name | H ras |
|---|---|
| Synonyms | C H RAS; Transforming protein p21; N ras; HRAS1; HRASP; C H ras 1 protein N terminal fragment (37 AA); C has/bas p21 protein; C ras Ki 2 protein… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11313892 | Liu R, Li B, Qiu M: Elevated production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha. Oncogene. 2001 Mar 22;20(12):1486-96. |
7(0,0,0,7) | Details |
| 10630619 | Wang C, Youssef J, Saran B, Rothberg PG, Cunningham ML, Molteni A, Badr M: Diminished energy metabolism and enhanced apoptosis in livers of B6C3F1 mice treated with the antihepatocarcinogen rotenone. Mol Cell Biochem. 1999 Nov;201(1-2):25-32. Conversely, mRNA of the proto-oncogene H-ras showed a decline of 35% after 3 days of rotenone treatment, and remained diminished for the duration of the experiment. |
6(0,0,1,1) | Details |
| 8240360 | Crowe RA, Taparowsky EJ, Crane FL: Ha-ras stimulates the transplasma membrane oxidoreductase activity of C3H10T1/2 cells. Biochem Biophys Res Commun. 1993 Oct 29;196(2):844-50. |
5(0,0,0,5) | Details |
| 19923925 | Yang D, Wang MT, Tang Y, Chen Y, Jiang H, Jones TT, Rao K, Brewer GJ, Singh KK, Nie D: Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS (Q61L). Cancer Biol Ther. 2010 Feb 21;9(2). First, mitochondrial respiration, as measured by mitochondrial consumption, was suppressed in NIH-3T3 cells transformed with H-Ras (Q61L). Second, oligomycin or rotenone did not reduce the cellular ATP levels in the H-Ras (Q61L) transformed cells, suggesting a diminished role of mitochondrial respiration in the cellular energy metabolism. |
4(0,0,0,4) | Details |
| 10559793 | Yang JQ, Li S, Domann FE, Buettner GR, Oberley LW: generation in v-Ha-ras-transduced human keratinocyte HaCaT cells. Mol Carcinog. 1999 Nov;26(3):180-8. generation was also inhibited by diphenylene iodonium, an inhibitor of flavoproteins, including oxidase, but not by rotenone, an inhibitor of the respiratory chain of the mitochondria. |
3(0,0,0,3) | Details |
| 19336726 | Woo JK, Choi DS, Tran HT, Gilbert BE, Hong WK, Lee HY: Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis. Cancer Prev Res (Phila Pa). 2009 Apr;2(4):361-9. Epub 2009 Mar 31. |
1(0,0,0,1) | Details |