Protein Information

Name glutamate pyruvate transaminases
Synonyms AAT1; AAT1; GPT; ALT 1; ALT1; Alanine aminotransferase; Alanine aminotransferase 1; GPT 1…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
19495970 Villa RF, Gorini A, Hoyer S: Effect of Ageing and Ischemia on Enzymatic Activities Linked to Krebs' Cycle, Electron Transfer Chain, Glutamate and Aminoacids Metabolism of Free and Intrasynaptic Mitochondria of Cerebral Cortex. Neurochem Res. 2009 Jun 4.

The maximum rate (V (max)) of the following enzyme activities: citrate synthase, malate dehydrogenase, succinate dehydrogenase for Krebs' cycle; NADH-cytochrome c reductase as total (integrated activity of Complex I-III), rotenone sensitive (Complex I) and cytochrome oxidase (Complex IV) for electron transfer chain; glutamate dehydrogenase, glutamate-oxaloacetate- and glutamate-pyruvate transaminases for glutamate metabolism were assayed in non-synaptic, perikaryal mitochondria and in two populations of intra-synaptic mitochondria, i.e., the light and heavy mitochondrial fraction.
31(0,1,1,1) Details
10425713 Obungu VH, Kiaira JK, Njogu RM, Olembo NK: Catabolism of proline by procyclic culture forms of Trypanosoma congolense. Comp Biochem Physiol B Biochem Mol Biol. 1999 May;123(1):59-65.

Rotenone had no effect on the rate of respiration except when the intact cells were first permeabilized by digitonin after which rotenone decreased the rate of respiration by 20-30%.
Enzymes involved in the catabolism of proline with high activities were: proline dehydrogenase, alpha-ketoglutarate dehydrogenase, succinate dehydrogenase, fumarase, NADP-linked malic enzyme, alanine aminotransferase and malate dehydrogenase.
1(0,0,0,1) Details
8158142 Veuthey AL, Tsacopoulos M, Millan de Ruiz L, Perrottet P: Cellular and subcellular localization of hexokinase, glutamate dehydrogenase, and alanine aminotransferase in the honeybee drone retina. J Neurochem. 1994 May;62(5):1939-46.

The distribution of enzymatic markers of mitochondria (succinate dehydrogenase, rotenone-insensitive cytochrome c reductase, and adenylate kinase) indicated that the outer mitochondrial membrane was partly damaged, but their distributions were different from that of hexokinase.
2(0,0,0,2) Details