| Name | ATG12 |
|---|---|
| Synonyms | APG12; APG12 autophagy 12 like; APG12 autophagy 12 like (S. cerevisiae); APG12 like; APG12L; ATG12; ATG12 autophagy related 12 homolog (S. cerevisiae); Apg12… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17457038 | Prigione A, Cortopassi G: Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12. Autophagy. 2007 Jul-Aug;3(4):377-80. Epub 2007 Jul 5. However, the bioenergetic inhibitor rotenone does not induce ATG12. |
6(0,0,0,6) | Details |
| 17651460 | Prigione A, Cortopassi G: Mitochondrial DNA deletions induce the -activated protein kinase energy stress pathway and result in decreased secretion of some proteins. Aging Cell. 2007 Oct;6(5):619-30. Epub 2007 Jul 26. Consistent with AMPK induction, its known targets SREBF1 (sterol regulatory element binding protein-1) and ATG12 were inhibited and induced, respectively. The defects in ATP synthesis, induction of the AMPK and SREBF1 transcripts, and decreased expression of ARL2 and secretion of OPG and FN were recapitulated by low doses of rotenone, demonstrating that they were a specific consequence of electron transport chain inhibition. |
1(0,0,0,1) | Details |