Protein Information

Name excitatory amino acid transporter 1
Synonyms EA6; Glial high affinity glutamate transporter; EAAT 1; EAAT1; Excitatory amino acid transporter 1; GLAST; GLAST 1; GLAST1…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
15342361 Beretta S, Mattavelli L, Sala G, Tremolizzo L, Schapira AH, Martinuzzi A, Carelli V, Ferrarese C: Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines. Brain. 2004 Oct;127(Pt 10):2183-92. Epub 2004 Sep 1.


Molecular and biochemical analyses showed that excitatory amino acid transporter 1 (EAAT1)/GLAST is the most active glutamate transporter in this cellular model.
3(0,0,0,3) Details
16959493 Beretta S, Wood JP, Derham B, Sala G, Tremolizzo L, Ferrarese C, Osborne NN: Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures. Neurobiol Dis. 2006 Nov;24(2):308-17. Epub 2006 Sep 7.


Primary rat retinal cultures were exposed to increasing concentrations of rotenone to titrate complex I inhibition.
0(0,0,0,0) Details