| Name | uncoupling protein 1 |
|---|---|
| Synonyms | Brown adipose tissue uncoupling protein; Mitochondrial brown fat uncoupling protein 1; SLC25A7; Thermogenin; UCP; UCP 1; UCP1; Uncoupling protein 1… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11342529 | Yamagishi SI, Edelstein D, Du XL, Kaneda Y, Guzman M, Brownlee M: Leptin induces mitochondrial production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem. 2001 Jul 6;276(27):25096-100. Epub 2001 May 7. Rotenone, thenoyltrifluoroacetone (TTFA), carbonyl m-chlorophenylhydrazone (CCCP), Mn (III) tetrakis (4- (MnTBAP), uncoupling protein-1 (UCP1) HVJ-liposomes, or manganese superoxide dismutase (MnSOD) HVJ-liposomes completely prevented the effect of leptin, suggesting that ROS arise from mitochondrial electron transport. |
31(0,1,1,1) | Details |
| 9688604 | Jezek P, Borecky J: Mitochondrial uncoupling protein may participate in futile cycling of and other monocarboxylates. Am J Physiol. 1998 Aug;275(2 Pt 1):C496-504. We studied and uniport via the uncoupling protein (UCP1) as a GDP-sensitive swelling in K+ salts induced by valinomycin or by monensin and carbonyl -p-(trifluoromethoxy) phenylhydrazone in Na+ salts. |
2(0,0,0,2) | Details |
| 10783895 | Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M: Normalizing mitochondrial production blocks three pathways of hyperglycaemic damage. Nature. 2000 Apr 13;404(6779):787-90. Here we show that this increase in reactive species is prevented by an inhibitor of electron transport chain complex II, by an uncoupler of oxidative phosphorylation, by uncoupling protein-1 and by manganese superoxide dismutase. |
1(0,0,0,1) | Details |
| 20209153 | de Meis L, Ketzer LA, da Costa RM, de Andrade IR, Benchimol M: Fusion of the endoplasmic reticulum and mitochondrial outer membrane in rats brown adipose tissue: activation of thermogenesis by Ca2+. PLoS One. 2010 Mar 2;5(3):e9439. Brown adipose tissue (BAT) mitochondria thermogenesis is regulated by uncoupling protein 1 (UCP 1), GDP and fatty acids. |
1(0,0,0,1) | Details |