Name | XIAP |
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Synonyms | API 3; API3; Apoptosis inhibitor 3; BIRC 4; BIRC4; Baculoviral IAP repeat containing protein 4; HILP; IAP Like protein… |
Name | rotenone |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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17035597 | Peng XH, Karna P, O'Regan RM, Liu X, Naithani R, Moriarty RM, Wood WC, Lee HY, Yang L: Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells. Mol Pharmacol. 2007 Jan;71(1):101-11. Epub 2006 Oct 11. Increasing evidence shows that the inhibitor of apoptosis (IAP) proteins survivin and XIAP are highly expressed in tumor cells but are absent or have very low levels of expression in normal adult tissues. |
2(0,0,0,2) | Details |
19633536 | Li Y, Rory Goodwin C, Sang Y, Rosen EM, Laterra J, Xia S: Camptothecin and Fas receptor agonists synergistically induce medulloblastoma cell death: ROS-dependent mechanisms. Anticancer Drugs. 2009 Oct;20(9):770-8. Western blot analyses showed that the combination of CH-11+CPT induced a significant decrease in XIAP levels. Moreover, the mitochondrial respiratory chain complex I inhibitor rotenone potentiated CH-11-induced apoptosis in DAOY cells. |
1(0,0,0,1) | Details |