Protein Information

Name IPF1
Synonyms GSF; Glucose sensitive factor; Homeodomain transcription factor IPF1; IDX 1; IDX1; IPF 1; IPF1; IUF 1…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
15151993 Gauthier BR, Brun T, Sarret EJ, Ishihara H, Schaad O, Descombes P, Wollheim CB: Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J Biol Chem. 2004 Jul 23;279(30):31121-30. Epub 2004 May 19.

Rotenone, an inhibitor of complex I, mimicked this effect.
Mutations in the transcription factor IPF1/PDX1 have been associated with type 2 diabetes.
1(0,0,0,1) Details