Name | APAF 1 |
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Synonyms | APAF1; Apaf 1; Apaf1; Apoptotic protease activating factor; Apoptotic protease activating factor1; Apoptotic protease activating factor 1; CED4; apoptotic peptidase activating factor… |
Name | rotenone |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16313906 | Pan T, Li X, Xie W, Jankovic J, Le W: mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells. FEBS Lett. 2005 Dec 19;579(30):6716-20. Epub 2005 Nov 21. We now show that attenuates rotenone (a potent complex I inhibitor)-induced apoptosis through the induction of heat shock protein 70, which may interact with apoptotic-protease-activating factor 1. |
-81(1,1,1,1) | Details |
16207793 | Potokar M, Kreft M, Chowdhury HH, Vardjan N, Zorec R: Subcellular localization of Apaf-1 in apoptotic rat pituitary cells. Am J Physiol Cell Physiol. 2006 Mar;290(3):C672-7. Epub 2005 Oct 5. We show herein that 2 h after triggering apoptosis with rotenone, Apaf-1 redistributed to the proximity of mitochondria. |
10(0,0,1,5) | Details |
16184340 | Ruggieri M, Avolio C, Scacco S, Pica C, Lia A, Zimatore GB, Papa S, Livrea P, Trojano M: Glatiramer acetate induces pro-apoptotic mechanisms involving Bcl-2, Bax and Cyt-c in peripheral lymphocytes from multiple sclerosis patients. J Neurol. 2006 Feb;253(2):231-6. Epub 2005 Sep 30. We analyzed the mitochondria membrane pro- (Bax) and anti-apoptotic (Bcl- 2) and cytosolic pro-apoptotic (Cyt-c, APAF-1) proteins expression in peripheral lymphocytes from relapsing-remitting (RR) MS patients during GA treatment. |
3(0,0,0,3) | Details |