| Name | adenylate cyclase |
|---|---|
| Synonyms | AH related protein; HCA2; ATP pyrophosphate lyase; Adenylate cyclase; Adenylyl cyclase soluble; HCA 2; RP1 313L4.2; SAC… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2982275 | Kiebzak GM, Yusufi AN, Kusano E, Braun-Werness J, Dousa TP: ATP and cAMP system in the in vitro response of microdissected cortical tubules to PTH. Am J Physiol. 1985 Jan;248(1 Pt 2):F152-9. Responsiveness of proximal convoluted tubule (PCT) and distal convoluted tubule (DCT) microdissected from mouse kidney to PTH, in terms of cAMP accumulation and stimulation of adenylate cyclase, was examined. In DCT, with ATP depleted by 1 microM rotenone, PTH failed to increase the cAMP, although 1 microM rotenone did not inhibit the adenylate cyclase activity. |
2(0,0,0,2) | Details |
| 2416223 | Kusano E, Murayama N, Werness JL, Christensen S, Homma S, Yusufi AN, Dousa TP: Effects of on the -sensitive cAMP metabolism in medullary tubules. Am J Physiol. 1985 Dec;249(6 Pt 2):F956-66. Added Ca2+ inhibited the AVP-stimulated adenylate cyclase in MCT and MAL (half-maximum approximately equal to 5 X 10 (-4) M Ca2+) and stimulated cAMP phosphodiesterase (cAMP-PDIE) in both MCT and in MAL (half-maximum approximately equal to 9 X 10 (-5) M Ca2+). |
2(0,0,0,2) | Details |
| 2833420 | Mitsunaga K, Fujino Y, Yasumasu I: Distributions of H+,K+-ATPase and Cl-,HCO3 (-)-ATPase in micromere-derived cells of sea urchin embryos. Differentiation. 1987;35(3):190-6. Activities of marker enzymes for plasma membrane, 5'-nucleotidase, Na+,K+-ATPase, and adenylate cyclase, were found to be high in the plasma membrane fraction. Considerable activity of rotenone-insensitive -cytochrome c reductase, a marker enzyme for microsome, was detectable in the microsome fraction. |
1(0,0,0,1) | Details |
| 2839496 | Connolly E, Nedergaard J: Beta-adrenergic modulation of Ca2+ uptake by isolated brown adipocytes. J Biol Chem. 1988 Aug 5;263(22):10574-82. The effect of (which had an EC50 of 140 nM) could be inhibited by beta-adrenergic blockade and could be mimicked by forskolin (an adenylate cyclase activator) and (a phosphodiesterase inhibitor). The effect of beta-adrenergic stimulation on Ca2+ uptake was not directly caused by the large increase in respiration that occurs in response to because the respiratory inhibitor rotenone did not affect the Ca2+ response of the cells to the hormone. |
1(0,0,0,1) | Details |
| 656472 | Wuytack F, Landon E, Fleischer S, Hardman JG: The accumulation in a microsomal fraction from porcine coronary artery smooth muscle. Biochim Biophys Acta. 1978 May 3;540(2):253-69. Adenylate cyclase appears to be a predominantly plasma membrane-bound enzyme. Rotenone-insensitive -cytochrome c reductase and phosphotransferase, two putative markers for internal membranes, give distinct banding patterns on on isopycnic centrifugation, indicating different intracellular localization. 6. |
1(0,0,0,1) | Details |
| 6256363 | Garbers DL: The elevation of cyclic AMP concentrations in flagella-less sea urchin sperm heads. J Biol Chem. 1981 Jan 25;256(2):620-4. The decline in ATP concentrations was slightly more rapid in the presence of rotenone, suggestive of some ATP synthetic capabilities of the isolated head preparation. 45Ca2+ uptake was increased by Nigericin elevated pH, and A23187 but was not appreciably altered by monensin. The isolated heads contained appreciable adenylate cyclase, cyclic AMP phosphodiesterase, cyclic GMP phosphodiesterase, guanylate cyclase, cyclic AMP-dependent protein kinase, and calmodulin. |
1(0,0,0,1) | Details |
| 3303974 | Stokes JB, Grupp C, Kinne RK: Purification of rat papillary collecting duct cells: functional and metabolic assessment. Am J Physiol. 1987 Aug;253(2 Pt 2):F251-62. As assessed by binding of the lectin Dolichos biflorus and determination of -sensitive adenylate cyclase and Na+-K+-ATPase, the enrichment of PCD cells over a crude papillary cell preparation was 1.8, 2.4, and 1.4, respectively. In the presence of rotenone, glycolysis increased by 56% and was able to maintain the cellular ATP level at 65% of control. |
1(0,0,0,1) | Details |
| 3021738 | Connolly E, Nanberg E, Nedergaard J: -induced Na+ influx in brown adipocytes is cyclic AMP-mediated. J Biol Chem. 1986 Nov 5;261(31):14377-85. Furthermore, total respiratory inhibition with rotenone, or total depletion of the medium with dithionite, did not prevent the normal -induced Na+ influx. |
0(0,0,0,0) | Details |
| 222966 | Hays RM, Franki N, Ross LS: Effect of metabolic inhibitors on -stimulated transport systems in the toad bladder. J Supramol Struct. 1979;10(2):175-84. In the present study, we have shown that inhibitors of oxidative metabolism (rotenone, dinitrophenol, and methylene blue) selectively inhibit either -stimulated water flow or -stimulated urea transport. |
0(0,0,0,0) | Details |