| Name | Siglec 8 |
|---|---|
| Synonyms | CD329 antigen; SAF 2; CDw329; SAF2; SIGLEC 8; SIGLEC8; SIGLEC8L; Sialic acid binding Ig like lectin 8… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17690326 | Nutku-Bilir E, Hudson SA, Bochner BS: Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathways. Am J Respir Cell Mol Biol. 2008 Jan;38(1):121-4. Epub 2007 Aug 9. Finally, both the mitochondrial electron transport inhibitor rotenone, and the ROS inhibitors diphenyleneiodonium and antimycin, completely inhibited Siglec-8-mediated apoptosis, even after IL-5 priming. |
87(1,1,1,7) | Details |
| 16157303 | Nutku E, Hudson SA, Bochner BS: Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injury. Biochem Biophys Res Commun. 2005 Oct 28;336(3):918-24. Rotenone and antimycin, inhibitors of mitochondrial respiratory chain components, completely inhibited apoptosis. |
7(0,0,0,7) | Details |