| Name | 6 phosphogluconate dehydrogenase |
|---|---|
| Synonyms | 6PGD; PGD; PGDH; Phosphogluconate dehydrogenase; Phosphogluconate dehydrogenases; 6 phospho D gluconate dehydrogenase; GNTZII; 6 phosphogluconic dehydrogenase… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 4404963 | Kather H, Rivera M, Brand K: Interrelationship and control of metabolism and lipogenesis in isolated fat-cells. Biochem J. 1972 Aug;128(5):1097-102. Treatment of cells with 6-aminonicotinamide caused an accumulation of indicating an inhibition of 6-phosphogluconate dehydrogenase. Rotenone, which is known to inhibit electron transport in the respiratory chain, blocked breakdown at the site of pyruvate dehydrogenase. |
1(0,0,0,1) | Details |
| 623294 | Richardson DK, Czech MP: Primary role of decreased fatty acid synthesis in insulin resistance of large rat adipocytes. Am J Physiol. 1978 Feb;234(2):E182-9. Furthermore, inhibition of mitochondrial oxidation and fatty acid synthesis in small cells by rotenone led to a secondary inhibition of shunt activity indicating a link between these two pathways. |
0(0,0,0,0) | Details |
| 6317750 | Kiyotaki C, Peisach J, Bloom BR: metabolism in cloned macrophage cell lines: dependence of production, metabolic and spectral analysis. J Immunol. 1984 Feb;132(2):857-66. O2- production in J774.16 cells was inhibited by some agents known to block mitochondrial electron transport before such as rotenone and tetrathiafulvalene, whereas antimycin A enhanced O2- production. |
0(0,0,0,0) | Details |