| Name | glial fibrillary acidic protein |
|---|---|
| Synonyms | GFAP; Glial fibrillary acidic protein; Glial fibrillary acidic proteins |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19644772 | Aoki E, Yokoyama H, Kimoto H, Yano R, Kato H, Araki T: Chronic administration with rotenone does not enhance MPTP neurotoxicity in C57BL/6 mice. J Mol Neurosci. 2010 May;41(1):17-24. Epub 2009 Jul 31. Our Western blot analysis study demonstrated that the change of tyrosine hydroxylase and glial fibrillary acidic protein protein levels in MPTP-treated mice was similar than that in MPTP + rotenone-treated animals. |
6(0,0,1,1) | Details |
| 17923380 | Radad K, Gille G, Rausch WD: Dopaminergic neurons are preferentially sensitive to long-term rotenone toxicity in primary cell culture. Toxicol In Vitro. 2008 Feb;22(1):68-74. Epub 2007 Sep 1. Astrocyte density was qualitatively evaluated by anti-glial fibrillary acidic protein (anti-GFAP) immunocytochemistry. |
1(0,0,0,1) | Details |
| 16543240 | Seo BB, Nakamaru-Ogiso E, Flotte TR, Matsuno-Yagi A, Yagi T: In vivo complementation of complex I by the yeast Ndi1 enzyme. J Biol Chem. 2006 May 19;281(20):14250-5. Epub 2006 Mar 16. We have shown previously that the single subunit rotenone-insensitive -quinone oxidoreductase (Ndi1) of Saccharomyces cerevisiae mitochondria can restore oxidation in complex I-deficient mammalian cells. The degree of neurodegeneration in the nigrostriatal system was assessed immunohistochemically through the analysis of tyrosine hydroxylase and glial fibrillary acidic protein. |
1(0,0,0,1) | Details |
| 17367952 | Samantaray S, Knaryan VH, Guyton MK, Matzelle DD, Ray SK, Banik NL: The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience. 2007 May 11;146(2):741-55. Epub 2007 Mar 23. Neuronal death was accompanied by abundant astrogliosis and microgliosis as evidenced from glial fibrillary acidic protein (GFAP)-immunoreactivity and OX-42-immunoreactivity, respectively, implicating an inflammatory component during neurodegeneration in SC. |
1(0,0,0,1) | Details |
| 18615648 | Schuh RA, Matthews CC, Fishman PS: Interaction of mitochondrial respiratory inhibitors and excitotoxins potentiates cell death in hippocampal slice cultures. J Neurosci Res. 2008 Nov 15;86(15):3306-13. The broad-spectrum insecticide rotenone, an inhibitor of complex I of the mitochondrial electron transport chain (ETC), gives rise to oxidative stress and bioenergetic failure. Immunohistochemical analysis using glial fibrillary acidic protein antibody determined that the cell death was preferentially neuronal. |
1(0,0,0,1) | Details |
| 16573651 | Casarejos MJ, Menendez J, Solano RM, Rodriguez-Navarro JA, Garcia de Yebenes J, Mena MA: Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. J Neurochem. 2006 May;97(4):934-46. Epub 2006 Mar 29. Indomethacin, a cyclo-oxygenase inhibitor, worsened the effects of ROT on tyrosine hydroxylase cells, apoptosis and astroglial (glial fibrillary acidic protein) cells. |
1(0,0,0,1) | Details |
| 16207877 | Abramov AY, Jacobson J, Wientjes F, Hothersall J, Canevari L, Duchen MR: Expression and modulation of an oxidase in mammalian astrocytes. . J Neurosci. 2005 Oct 5;25(40):9176-84. This was independent of mitochondrial ROS production, because it was unaffected by mitochondrial depolarization with rotenone and oligomycin. Seeking evidence for the expression and function of the enzyme in primary hippocampal astrocytes, we confirmed the expression of the subunits of the phagocyte NADPH oxidase by Western blot analysis and by immunofluorescence and coexpression with the astrocyte-specific marker glial fibrillary acidic protein both in cultures and in vivo. |
1(0,0,0,1) | Details |
| 19900533 | Ishido M, Suzuki J: Inhibition by rotenone of mesencephalic neural stem-cell migration in a neurosphere assay in vitro. Toxicol In Vitro. 2010 Mar;24(2):552-7. Epub 2009 Nov 10. The migrating populations comprised cells that were positive for nestin, microtubule-associated proteins, and glial fibrillary acidic protein. |
1(0,0,0,1) | Details |