| Name | Q10 |
|---|---|
| Synonyms | AGO 2; PPD; AGO2; Argonaute 2; EIF2C2; Eukaryotic translation initiation factor 2C 2; PAZ Piwi domain protein; Q10… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16750479 | Sharma SK, El Refaey H, Ebadi M: Complex-1 activity and 18F- uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of Brain Res Bull. 2006 Jun 15;70(1):22-32. Epub 2005 Dec 27. Direct exposure of rotenone also reduced coenzyme Q10, complex-1 activity, and mitochondrial membrane potential in SK-N-SH cells. |
81(1,1,1,1) | Details |
| 1333196 | Ramsay RR, Singer TP: Relation of generation and lipid peroxidation to the inhibition of -Q oxidoreductase by rotenone, piericidin A, and MPP+. Biochem Biophys Res Commun. 1992 Nov 30;189(1):47-52. The addition of to submitochondrial particles inhibited by agents which interrupt electron transport from -Q oxidoreductase (Complex I) to Q10 (rotenone, piericidin A, and MPP+) results in formation and lipid peroxidation. |
31(0,1,1,1) | Details |
| 18817789 | Abdin AA, Hamouda HE: Mechanism of the neuroprotective role of with or without in rotenone-induced parkinsonism. Neuropharmacology. 2008 Dec;55(8):1340-6. Epub 2008 Sep 10. Oral administration of Co Q10 in a low dose 200 mg/kg/day (group III) or a high dose 600 mg/kg/day (group IV), resulted in amelioration of the mitochondrial induced apoptosis by dose-dependent restoration of striatal complex I activity, ATP levels with temperate increase in expression of Bcl-2 as well as decrease in catalepsy score. |
3(0,0,0,3) | Details |
| 1171697 | Wang CC: Studies of the mitochondria from Eimeria tenella and inhibition of the electron transport by quinolone coccidiostats. Biochim Biophys Acta. 1975 Aug 11;396(2):210-9. The mitochondrial respiration was inhibited by azide, antimycin A, and 2-heptyl-4-hydroxyquinoline-N-oxide, but was relatively resistant to rotenone and amytal. |
0(0,0,0,0) | Details |