| Name | SNAP |
|---|---|
| Synonyms | RIC 4; RIC4; SEC 9; SEC9; SNAP; SNAP 25; SNAP25; SUP… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16584707 | Borutaite V, Brown GC: S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial peroxide production. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):562-6. Epub 2006 Mar 23. Specific inhibition of complex I with rotenone increased H2O2 production to a similar extent as that caused by SNAP. |
32(0,1,1,2) | Details |
| 9586799 | Tsai MJ, Lee EH: donors protect cultured rat astrocytes from 1-methyl-4-phenylpyridinium-induced toxicity. Free Radic Biol Med. 1998 Mar 15;24(5):705-13. NO. donors and analogues were also tested against damage produced by rotenone, an irreversible complex I inhibitor. Because (NO.) is suggested to be cytoprotective, we examined the effects of nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP), and 3-morpholinosydnonimine (SIN-1) on MPP+-induced toxicity in astrocytes. |
2(0,0,0,2) | Details |
| 9846647 | Guidarelli A, Clementi E, Sciorati C, Cantoni O: The mechanism of the -mediated enhancement of tert-butylhydroperoxide-induced DNA single strand breakage. Br J Pharmacol. 1998 Nov;125(5):1074-80. The DNA lesions generated by tB-OOH alone, or combined with SNAP, were repaired with superimposable kinetics and were insensitive to anti-oxidants and scavengers but suppressed by iron chelators. 3. The SNAP- or GSNO-mediated enhancement of the tB-OOH-induced DNA cleavage was abolished by the respiratory chain inhibitors rotenone and myxothiazol and was not apparent in respiration-deficient cells. 5. |
1(0,0,0,1) | Details |
| 7639736 | Volk T, Ioannidis I, Hensel M, deGroot H, Kox WJ: Endothelial damage induced by synergism with reactive species. Biochem Biophys Res Commun. 1995 Aug 4;213(1):196-203. S-Nitroso-N-acetyl-DL-penicillamine (SNAP), 3-morpholinosydnonimine-N-ethylcarbamide (SIN-1) and sodiumnitroprusside (SNP) were used as NO.-donating agents. Non toxic doses of KCN (1 mM), antimycin A (1 microM), and rotenone (0.5 microM) in order to increase endogeneously produced reactive species increased toxic effects by 20-30% (p < 0.05). |
1(0,0,0,1) | Details |
| 17961592 | Gautier M, Zhang H, Fearon IM: formation mediates LPC-induced augmentation of cardiac late currents. J Mol Cell Cardiol. 2008 Feb;44(2):241-51. Epub 2007 Sep 21. However, SNAP enhanced TTX-sensitive recombinant and native I (L) Na in the presence of pyrogallol, suggesting peroxynitrite formation as a mediator of the response to LPC. Inhibitors of the mitochondrial electron transport chain (rotenone, TTFA and myxothiazol) were without effect on LPC responses. |
1(0,0,0,1) | Details |
| 10987825 | Bal-Price A, Brown GC: -induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J Neurochem. 2000 Oct;75(4):1455-64. A 24-h incubation of PC12 cells with NO donors (SNAP or NOC-18) or specific inhibitors of mitochondrial respiration (myxothiazol, rotenone, or azide), in the absence of caused total ATP depletion and resulted in 80-100% necrosis. |
0(0,0,0,0) | Details |