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Ichikawa H, Kokura S, Aw TY: Role of endothelial mitochondria in oxidant production and modulation of neutrophil adherence. J Vasc Res. 2004 Sep-Oct;41(5):432-44. Epub 2004 Oct 12.
Blockade of electron transport in antimycin A and A/R exposed cells with rotenone, amytal or thenoyltrifluoroacetate, but not myxothiazol, prevented neutrophil adhesion, confirming a role for mitochondrial ROS. Peak surface expression of the endothelial cell adhesion molecules correlated with peak adhesions at phases 1 and 2. |
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