| Name | NARP |
|---|---|
| Synonyms | NARP; NP II; NP2; NPTX 2; NPTX2; Neuronal pentraxin II; Neuronal pentraxin 2; Neuronal pentraxin 2 precursor… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17276738 | Fujita Y, Ito M, Nozawa Y, Yoneda M, Oshida Y, Tanaka M: CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations. Mitochondrion. 2007 Feb-Apr;7(1-2):80-8. Epub 2006 Dec 3. |
3(0,0,0,3) | Details |
| 16815102 | Cortopassi G, Danielson S, Alemi M, Zhan SS, Tong W, Carelli V, Martinuzzi A, Marzuki S, Majamaa K, Wong A: Mitochondrial disease activates transcripts of the unfolded protein response and cell cycle and inhibits vesicular secretion and oligodendrocyte-specific transcripts. Mitochondrion. 2006 Aug;6(4):161-75. Epub 2006 May 24. To examine the extent to which the transcriptional profile was shared among 5 mitochondrial diseases (LHON, FRDA, MELAS, KSS, and NARP), we microarrayed mutant and control groups in N-tera2, SH-SY5Y, lymphoblasts, fibroblasts, myoblasts, muscle, and osteosarcoma cybrids. Mitochondrial disease activated multiple transcripts of the unfolded protein response (UPR), and of the cell cycle pathway, and low doses of the mitochondrial inhibitor rotenone induced UPR transcripts in the absence of cell death. |
1(0,0,0,1) | Details |
| 8476414 | Tatuch Y, Robinson BH: The mitochondrial DNA mutation at 8993 associated with NARP slows the rate of synthesis in isolated lymphoblast mitochondria. Biochem Biophys Res Commun. 1993 Apr 15;192(1):124-8. Rates of synthesis with / /rotenone, /N'N'N'N' tetramethyl phenylene diamine were reduced to 67%, 58% and 54% of the control rates, respectively. |
1(0,0,0,1) | Details |