| Name | DCIP |
|---|---|
| Synonyms | DCIP; Mop5; Dendritic cell derived IFNG induced protein; HDDC 1; HDDC1; MOP 5; Mg11; Monocyte protein 5… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19097788 | Dong CK, Patel V, Yang JC, Dvorin JD, Duraisingh MT, Clardy J, Wirth DF: Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. Bioorg Med Chem Lett. 2009 Feb 1;19(3):972-5. Epub 2008 Nov 24. Plasmodium falciparum NDH2 (pfNDH2) is a non- pumping, rotenone-insensitive alternative enzyme to the multi-subunit NADH:ubiquinone oxidoreductases (Complex I) of many other eukaryotes. Recombinantly expressed pfNDH2 prefers coenzyme (0) as an acceptor substrate, and can also use the artificial electron acceptors, and dichlorophenol-indophenol (DCIP). |
1(0,0,0,1) | Details |
| 6317663 | Kang D, Narabayashi H, Sata T, Takeshige K: Kinetics of formation by respiratory chain - dehydrogenase of bovine heart mitochondria. J Biochem. 1983 Oct;94(4):1301-6. The plots of the -dependent activity of rotenone-treated submitochondrial particles were also biphasic. The double reciprocal plots of - and -dependent 2,6-dichlorophenolindophenol (DCIP) reductase activities of Complex I were linear and the plots of the -forming activities against the DCIP reductase activities were biphasic. |
1(0,0,0,1) | Details |
| 12904542 | Nagata K, Nagata Y, Sato T, Fujino MA, Nakajima K, Tamura T: D- and and as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels. Microbiology. 2003 Aug;149(Pt 8):2023-30. These respiratory activities were inhibited by rotenone and antimycin A at low concentrations. Whole cells showed 2,6-dichlorophenolindophenol (DCIP)-reducing activities with D- and and D- as substrates, suggesting that removed from these amino acids also participated in uptake by the whole cells. |
1(0,0,0,1) | Details |
| 19059197 | Fato R, Bergamini C, Bortolus M, Maniero AL, Leoni S, Ohnishi T, Lenaz G: Differential effects of mitochondrial Complex I inhibitors on production of reactive species. Biochim Biophys Acta. 2009 May;1787(5):384-92. Epub 2008 Nov 14. Moreover the two classes of Complex I inhibitors have an opposite effect on the increase of -DCIP reduction induced by short chain quinones: only Class B inhibitors allow this increase, indicating the presence of a Rotenone-sensitive but Stigmatellin-insensitive semiquinone species in the active site of the enzyme. |
31(0,1,1,1) | Details |
| 19520091 | Long J, Ma J, Luo C, Mo X, Sun L, Zang W, Liu J: Comparison of two methods for assaying complex I activity in mitochondria isolated from rat liver, brain and heart. Life Sci. 2009 Aug 12;85(7-8):276-80. Epub 2009 Jun 9. KEY FINDINGS: The DCIP method gave a higher enzyme sensitivity and comparable rotenone sensitivity in heart mitochondria while the method gave higher rotenone sensitivity with a relatively lower enzyme activity in the brain and liver mitochondria. |
13(0,0,2,3) | Details |
| 12390527 | Wright MV, Kuhn TB: CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability. J Neurochem. 2002 Nov;83(3):655-64. In this investigation, extracellular reduction of 2,6-dichloroindophenol (DCIP) and ferricyanide (FeCN) were measured as indicators of trans-plasma membrane electron transport by chick forebrain neurons. |
1(0,0,0,1) | Details |
| 2871147 | Sugiyama Y, Fujita T, Matsumoto M, Okamoto K, Imada I: Effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in brain mitochondria from rats and dogs. J Pharmacobiodyn. 1985 Dec;8(12):1006-17. These facts and results of inhibitor analysis suggest that the action site of CV-2619 is -linked complex I in the mitochondrial respiratory chain and is different from that of inhibitors of oxidative phosphorylation such as rotenone, oligomycin and 2,4-dinitrophenol. |
0(0,0,0,0) | Details |