Protein Information

Name BCL2 associated X protein
Synonyms Apoptosis regulator BAX; BAX; BCL2 associated X protein; BCL2 associated X protein isoform beta; Bax zeta; BCL2 associated X proteins; BCL2 associated X protein isoform betas; Bax zetas

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
19885011 Kim HJ, Song JY, Park HJ, Park HK, Yun DH, Chung JH: Naringin Protects against Rotenone-induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells. Korean J Physiol Pharmacol. 2009 Aug;13(4):281-5. Epub 2009 Aug 31.

Naringin also blocked rotenone-induced phosphorylation of Jun NH2-terminal protein kinase (JNK) and P38, and prevented changes in B-cell CLL/lymphoma 2 (BCL2) and BCL2-associated X protein (BAX) expression levels.
81(1,1,1,1) Details
19723537 Park HJ, Kim HJ, Park HK, Chung JH: Protective effect of histamine H2 receptor antagonist ranitidine against rotenone-induced apoptosis. Neurotoxicology. 2009 Nov;30(6):1114-9. Epub 2009 Aug 31.

Ranitidine also prevented the down-regulation of B-cell CLL/lymphoma 2 (BCL2) and the up-regulation of BCL2-associated X protein (BAX) by rotenone.
6(0,0,1,1) Details