Protein Information

Name AMPH
Synonyms AMPH; AMPH 1; AMPH1; Amphiphysin; Amphyphysin I; Amphiphysins; Amphyphysin Is

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
11198300 Lotharius J, O'Malley KL: Role of mitochondrial dysfunction and dopamine-dependent oxidative stress in amphetamine-induced toxicity. Ann Neurol. 2001 Jan;49(1):79-89.

In contrast, when primary cultures of dopaminergic neurons were exposed to AMPH in the presence of subtoxic doses of the mitochondrial complex I inhibitor rotenone, cell death was dramatically increased, mimicking the effects of a known parkinsonism-inducing toxin.
85(1,1,1,5) Details