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Katsuragi T, Sato C, Usune S, Ueno S, Segawa M, Migita K: Caffeine-inducible ATP release is mediated by Ca2+-signal transducing system from the endoplasmic reticulum to mitochondria. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jul;378(1):93-101. Epub 2008 May 1.
The expression of messenger RNA from only RyR-2 was detected in the cells.
Furthermore, the induced release was attenuated by mitochondrial inhibitors, rotenone and oligomycin and by Cl- channel blockers, niflumic acid, and 5-nitro-2-(3-phenylpropylamino)-benzoic acid. |
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