| Name | Substance P |
|---|---|
| Synonyms | Hs.2563; PPT; NK2; NKA; NKNA; Neurokinin 1; Neurokinin 2; Neurokinin A… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15544846 | Springer J, Pleimes D, Scholz FR, Fischer A: Substance P mediates AP-1 induction in A549 cells via reactive species. Regul Pept. 2005 Jan 15;124(1-3):99-103. The likely source of ROS are the mitochondria as rotenone inhibited AP-1 induction and the p47phox subunit of the oxidase complex, responsible for ROS generation in phagocytotic cells, was not expressed in A549 cells assayed by RT-PCR. |
2(0,0,0,2) | Details |
| 8156634 | Close LA, Bowman PS, Paul RJ: Reoxygenation-induced relaxation of coronary arteries. Circ Res. 1994 May;74(5):870-81. The reoxygenation relaxation was, however, sensitive to very low levels of and was inhibited by and rotenone, suggesting an involvement of mitochondrial metabolism. Interestingly, the relaxation response to reoxygenation, similar to that for substance P, could be restored in denuded arteries by coupling with an endothelium-intact donor artery. |
1(0,0,0,1) | Details |
| 7824183 | Brouillet E, Henshaw DR, Schulz JB, Beal MF: Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and Neurosci Lett. 1994 Aug 15;177(1-2):58-62. In the present study, we show that and the specific complex I inhibitor rotenone produces a similar neurochemical profile in the striatum, consistent with an effect of AOAA on energy metabolism. Lesions produced by AOAA were dose-dependently blocked by MK-801, with complete protection against and substance P depletions at a dose of 3 mg/kg. |
1(0,0,0,1) | Details |