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Ichikawa H, Takagi T, Uchiyama K, Higashihara H, Katada K, Isozaki Y, Naito Y, Yoshida N, Yoshikawa T: Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced intestinal mucosal damage in rats. Redox Rep. 2004;9(6):313-6.
Intraluminal hemoglobin and protein levels, the mucosal content of thiobarbituric acid-reactive substances (TBARS), the mucosal myeloperoxidase activity, and the content of inflammatory cytokines (CINC-1, TNF-alpha) were all significantly increased from mean basal levels after 60 min of reperfusion. |
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