Protein Information

Name matrix metalloprotease 2
Synonyms 72 kDa gelatinase; 72 kDa type IV collagenase; 72 kDa type IV collagenase precursor; CLG 4; CLG4; CLG4A; Collagenase type 4A; Gelatinase A…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
11929863 Zhang HJ, Zhao W, Venkataraman S, Robbins ME, Buettner GR, Kregel KC, Oberley LW: Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. J Biol Chem. 2002 Jun 7;277(23):20919-26. Epub 2002 Apr 2.

Treatment of MCF-7 cells with antimycin A or rotenone increased intracellular ROS production and MMP-2 activation simultaneously.
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12236590 Das S, Chakraborti T, Mandal M, Mandal A, Chakraborti S: Role of membrane-associated Ca+ dependent matrix metalloprotease-2 in the oxidant activation of Ca2+Atpase by tertiary butylhydroperoxide. Mol Cell Biochem. 2002 Aug;237(1-2):85-93.

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