| 18586549 |
Koch A, Lehmann-Horn K, Dachsel JC, Gasser T, Kahle PJ, Lucking CB: Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells. Parkinsonism Relat Disord. 2009 Mar;15(3):220-5. Epub 2008 Jun 30.
We systematically investigated whether PD-related stresses including MG132 and epoxomicin (proteasomal impairment), tunicamycin (unfolded protein stress), and rotenone (mitochondrial dysfunction) resulted in expressional changes of parkin and other E3 ubiquitin ligases (dorfin, SIAH-1). |
6(0,0,1,1) |
Details |