| Name | guanylate cyclase |
|---|---|
| Synonyms | AMDM; Natriuretic peptide receptor; ANP B; ANPRB; Atrial natriuretic peptide B type receptor; Atrial natriuretic peptide receptor B; Atrial natriuretic peptide receptor B precursor (ANP B) (ANPRB) (GC B) (Guanylate cyclase B); Atrionatriuretic peptide receptor B… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6162485 | Dohi T, Murad F: Effects of and other metabolites on cyclic GMP levels in incubations of rat hepatocytes and kidney cortex. Biochim Biophys Acta. 1981 Feb 18;673(1):14-25. and mepacrine inhibited soluble and particulate guanylate cyclase from rat liver while cycloserine and increased guanylate cyclase activity. Rotenone, oligomycin, antimycin, dinitrophenol, KCN, and arsenate decreased GTP and ATP, basal cyclic GMP and the effect, but did not alter cyclic AMP. |
2(0,0,0,2) | Details |
| 11531163 | Bergemann C, Loken C, Becker C, Graf B, Hamidizadeh M, Fischer Y: Inhibition of transport by cyclic GMP in cardiomyocytes. Life Sci. 2001 Aug 10;69(12):1391-406. Blockade of endogenous formation with the guanylate cyclase inhibitor 1H-[1,2,4] oxadiazolo [4,3-a] quinoxalin-1-one (ODQ, 10 microM) significantly increased basal and insulin-dependent transport (by 25%), whereas addition of the guanylate cyclase activator 3-(5'-hydroxymethyl-2'furyl)-1-benzylindazol (YC-1, 30 microM) produced a depression of transport (by 20%). |
1(0,0,0,1) | Details |
| 6140917 | Tsai SC, Adamik R, Manganiello VC, Vaughan M: Regulation of activity of purified guanylate cyclase from liver that is unresponsive to Biochem J. 1983 Dec 1;215(3):447-55. Rotenone (0.6 mM) inhibited activity with to a greater extent than with nitrosylhaemoglobin. |
2(0,0,0,2) | Details |
| 15377279 | Kollau A, Hofer A, Russwurm M, Koesling D, Keung WM, Schmidt K, Brunner F, Mayer B: Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of Biochem J. 2005 Feb 1;385(Pt 3):769-77. Lack of effect of the mitochondrial poisons, rotenone and myxothiazol, suggested that reduction by components of the respiratory chain is not essential to sGC activation. |
1(0,0,0,1) | Details |
| 6256363 | Garbers DL: The elevation of cyclic AMP concentrations in flagella-less sea urchin sperm heads. J Biol Chem. 1981 Jan 25;256(2):620-4. The decline in ATP concentrations was slightly more rapid in the presence of rotenone, suggestive of some ATP synthetic capabilities of the isolated head preparation. 45Ca2+ uptake was increased by Nigericin elevated pH, and A23187 but was not appreciably altered by monensin. The isolated heads contained appreciable adenylate cyclase, cyclic AMP phosphodiesterase, cyclic GMP phosphodiesterase, guanylate cyclase, cyclic AMP-dependent protein kinase, and calmodulin. |
1(0,0,0,1) | Details |
| 16300973 | Bal-Price A, Gartlon J, Brown GC: stimulates PC12 cell proliferation via and inhibits at higher concentrations mainly via energy depletion. Nitric Oxide. 2006 May;14(3):238-46. Epub 2005 Nov 21. Cytostatic concentrations of DETA/NO strongly inhibited respiration of PC12 cells, and specific respiratory inhibitors (rotenone, myxothiazol, or azide) caused complete cytostasis. |
0(0,0,0,0) | Details |