Protein Information

Name LRRK1
Synonyms LRRK 1; LRRK1; Leucine rich repeat kinase 1; Leucine rich repeat serine/threonine protein kinase 1; Roco1; Leucine rich repeat kinase 1s; Leucine rich repeat serine/threonine protein kinase 1s; Roco1s

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
18322385 Wolozin B, Saha S, Guillily M, Ferree A, Riley M: Investigating convergent actions of genes linked to familial Parkinson's disease. Neurodegener Dis. 2008;5(3-4):182-5. Epub 2008 Mar 6.

OBJECTIVES: To investigate how expressing wild-type or G2019S LRRK2 modifies cellular responses to rotenone, a mitochondrial toxin.
CONCLUSIONS: These data suggest that LRRK1/2 regulate mitochondrial physiology.
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