Protein Information

Name Kir2.3
Synonyms HIR; HIRK 2; HIRK2; HRK 1; HRK1; Hippocampal inward rectifier; Hippocampal inward rectifier potassium channel; Inward rectifier K(+) channel Kir2.3…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
18619942 Wang G, Zeng J, Shen CY, Wang ZQ, Chen SD: Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway. Biochem Biophys Res Commun. 2008 Sep 19;374(2):204-9. Epub 2008 Jul 11.

Here we show that Kir2.3 overexpression can protect against rotenone-induced apoptosis in cell models in the neurodegenerative process, suggesting Kir2.3's general neuroprotective function.
39(0,1,2,4) Details