Name | histone deacetylases (protein family or complex) |
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Synonyms | Histone deacetylase; Histone deacetylases |
Name | rotenone |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19626387 | Monti B, Gatta V, Piretti F, Raffaelli SS, Virgili M, Contestabile A: rotenone rat model of Parkinson's disease: involvement of alpha-synuclein. Neurotox Res. 2010 Feb;17(2):130-41. Epub 2009 Jul 21. Among its many cellular targets, VPA has been recently demonstrated to be an effective inhibitor of histone deacetylases. |
is neuroprotective in the 2(0,0,0,2) | Details |
19835929 | Wang Y, Wang X, Liu L, Wang X: HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. Neurosci Lett. 2009 Dec 31;467(3):212-6. Epub 2009 Oct 14. Histone deacetylase (HDAC) inhibitors have been shown associated with neurodegenerative diseases. Pre-treatment with TSA resulted in exacerbated damage to dopaminergic neurons induced by 1-methyl-4-phenylpyridinium and rotenone. |
1(0,0,0,1) | Details |