| Name | Glutathione S transferase pi |
|---|---|
| Synonyms | DFN 7; PI; DFN7; FAEES 3; FAEES3; GST class pi; GST3; GSTP 1… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19126423 | Perez-Carreon JI, Dargent C, Merhi M, Fattel-Fazenda S, Arce-Popoca E, Villa-Trevino S, Rouimi P: Tumor promoting and co-carcinogenic effects in medium-term rat hepatocarcinogenesis are not modified by co-administration of 12 pesticides in mixture at acceptable daily intake. Food Chem Toxicol. 2009 Mar;47(3):540-6. Epub 2008 Dec 24. We performed a 12 commercially available pesticides combination with alachlor, atrazine, carbofuran, chlorpyrifos, diazinon, dicofol, endosulfan, iprodione, mancozeb, maneb, procymidone and rotenone. Co-carcinogenic effect and promoting activity were evaluated using gamma-glutamyl transpeptidase (GGT) positive altered hepatocyte foci, as well, protein and mRNA levels of glutathione S-transferase P (GSTP) in liver extracts as molecular biomarkers of carcinogenic effects. |
1(0,0,0,1) | Details |
| 19269317 | Goto S, Kawakatsu M, Izumi S, Urata Y, Kageyama K, Ihara Y, Koji T, Kondo T: Glutathione S-transferase pi localizes in mitochondria and protects against oxidative stress. Free Radic Biol Med. 2009 May 15;46(10):1392-403. Epub 2009 Mar 6. Chemicals generating reactive species, such as rotenone and antimycin A, decreased cell viability and reduced mitochondrial membrane potential. |
1(0,0,0,1) | Details |