| Name | IL 3 |
|---|---|
| Synonyms | Hematopoietic growth factor; IL 3; IL3; Interleukin 3; Interleukin 3 precursor; MCGF; MULTI CSF; Mast cell growth factor… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17102131 | Brown NM, Martin SM, Maurice N, Kuwana T, Knudson CM: Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells. J Biol Chem. 2007 Jan 26;282(4):2144-55. Epub 2006 Nov 13. Following interleukin (IL)-3 withdrawal in FL5.12 cells, Bax undergoes a conformational change that results in its mitochondria targeting, cytochrome c release, activation of caspase-9, and apoptosis. Furthermore, the "rescued" cells were resistant to rotenone, an inhibitor of mitochondrial respiration. |
2(0,0,0,2) | Details |
| 8390225 | Berridge MV, Tan AS: Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys. 1993 Jun;303(2):474-82. -dependent mitochondrial MTT reduction was inhibited by 80% with chlorpromazine, 70% by antimycin A, and 85-90% by thenoyltrifluoracetone (TTFA), but inhibition was not observed with rotenone at < or = 2 microM, Amytal, or azide. |
0(0,0,0,0) | Details |