| Name | mineralocorticoid receptor |
|---|---|
| Synonyms | Aldosterone receptor; MCR; MLR; MR; Mineralocorticoid receptor; NR3C2; Mineralocorticoid receptors |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19339632 | Huang S, Zhang A, Ding G, Chen R: -induced mesangial cell proliferation is mediated by EGF receptor transactivation. Am J Physiol Renal Physiol. 2009 Jun;296(6):F1323-33. Epub 2009 Apr 1. Pretreatment with the antioxidant N-acetyl- catalase, SOD, mitochondrial respiratory chain complex I inhibitor rotenone (Rot), oxidase inhibitor apocynin, and DPI significantly inhibited Aldo-stimulated MC proliferation as well as EGFR transactivation. This increase in proliferation was blocked by inhibition of the mineralocorticoid receptor (MR). |
1(0,0,0,1) | Details |
| 17596522 | Zhang A, Jia Z, Guo X, Yang T: induces epithelial-mesenchymal transition via ROS of mitochondrial origin. Am J Physiol Renal Physiol. 2007 Sep;293(3):F723-31. Epub 2007 Jun 27. The EMT was completely blocked by the selective mineralocorticoid receptor (MR) antagonist eplerenone. Aldo-induced oxidative stress and EMT were both abolished by the mitochondrial respiratory chain complex I inhibitor rotenone, but not the oxidase inhibitor apocynin. |
1(0,0,0,1) | Details |