Protein Information

Name 2 methyl branched chain acyl CoA dehydrogenase
Synonyms 2 MEBCAD; 2 methyl branched chain acyl CoA dehydrogenase; 2 methyl branched chain acyl Coenzyme A dehydrogenase; 2 methylbutyryl CoA dehydrogenase; 2 methylbutyryl Coenzyme A dehydrogenase; ACAD 7; ACAD7; ACADSB…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
3988734 Komuniecki R, Fekete S, Thissen-Parra J: Purification and characterization of the 2-methyl branched-chain Acyl-CoA dehydrogenase, an enzyme involved in NADH-dependent enoyl-CoA reduction in anaerobic mitochondria of the nematode, Ascaris suum. J Biol Chem. 1985 Apr 25;260(8):4770-7.

Incubations of A. suum submitochondrial particles, NADH, tiglyl-CoA, purified A. suum electron-transfer flavoprotein, and the 2-methyl branched-chain acyl-CoA dehydrogenase resulted in the rotenone-sensitive, dehydrogenase-dependent formation of 2-methylbutyryl-CoA.
8(0,0,1,3) Details
6704106 Komuniecki R, Fekete S, Thissen J: 2-Methylbutyryl CoA dehydrogenase from mitochondria of Ascaris suum and its relationship to NADH-dependent 2-methylcrotonyl CoA reduction. Biochem Biophys Res Commun. 1984 Feb 14;118(3):783-8.

In fact, incubations of A. suum mitochondrial membranes with electron-transfer flavoprotein, 2-methylbutyryl CoA dehydrogenase, 2-methylcrotonyl CoA and NADH resulted in a substantial, rotenone-sensitive, 2-methylbutyrate synthesis.
32(0,1,1,2) Details