| Name | alpha interferon |
|---|---|
| Synonyms | Alpha interferon; IFNA; IFL; IFN; IFN alpha; IFN leukocytic; IFNA 1; IFNA1… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18840762 | Eley HL, Russell ST, Tisdale MJ: Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1417-26. Epub 2008 Oct 7. Both tumor necrosis factor-alpha (TNF-alpha)/interferon-gamma (IFN-gamma) and angiotensin II (ANG II) induced an increase in total protein degradation in murine myotubes, which was completely attenuated by treatment with (HMB; 50 microM). Formation of ROS was attenuated by rotenone, an inhibitor of the mitochondrial electron transport chain, nitro- methyl ester, an inhibitor of synthase, and SB 203580, a specific inhibitor of p38 mitogen-activated protein kinase (p38 MAPK), which also attenuated total protein degradation. |
1(0,0,0,1) | Details |
| 11710721 | Sambo P, Baroni SS, Luchetti M, Paroncini P, Dusi S, Orlandini G, Gabrielli A: Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive species generation through the oxidase complex pathway. Arthritis Rheum. 2001 Nov;44(11):2653-64. This suppression was not seen with rotenone, a mitochondrial oxidase inhibitor, or allopurinol, a xanthine oxidase inhibitor. |
0(0,0,0,0) | Details |