| Name | transcription factor E2F |
|---|---|
| Synonyms | E2F transcription factor 1; RBP 3; RBP3; E2F 1; E2F1; PBR 3; PBR3; PRB binding protein E2F1… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17343987 | Alvira D, Tajes M, Verdaguer E, de Arriba SG, Allgaier C, Matute C, Trullas R, Jimenez A, Pallas M, Camins A: Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons. Neuroscience. 2007 Apr 25;146(1):350-65. Epub 2007 Mar 7. We show a distinct increase in the expression of the cell cycle proteins cyclin D, cyclin E, cdk2, cdk4 and the transcription factor E2F-1 following a MPP+ treatment of CGNs. |
2(0,0,0,2) | Details |
| 12460790 | Murillo G, Salti GI, Kosmeder JW 2nd, Pezzuto JM, Mehta RG: Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. Eur J Cancer. 2002 Dec;38(18):2446-54. Since hypophosphorylated pRb binds to and inactivates E2F1, additional studies were performed and downregulation of E2F1 was observed after 24 h of treatment with deguelin. |
1(0,0,0,1) | Details |