Protein Information

Name cytochrome c oxidase is
Synonyms COI; COX1; COX_I; Cytochrome c oxidase I; Cytochrome c oxidase polypeptide I; MT CO1; MTCO 1; MTCO1…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
6245185 Scholte HR, Busch HF: Early changes of muscle mitochondria in Duchenne dystrophy. J Neurol Sci. 1980 Mar;45(2-3):217-34.

The specific activities of the matrix enzymes propionyl-CoA carboxylase and glutamate dehydrogenase are 1.8 and 2.8 times increased, the inner membrane enzyme cytochrome c oxidase is 2.8 times increased, the inner membrane enzyme cytochrome c oxidase is 2.8 times increased.
Muscles from boys and adults without neuromuscular disease were treated likewise. (2) In adults, muscle possesses a significantly higher specific activity (on protein basis) of monoamine oxidase and rotenone-insenitive NADH-cytochrome c reductase (RINCR) than in boys.
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8631334 Volkel S, Grieshaber MK: Mitochondrial sulfide oxidation in Arenicola marina. Eur J Biochem. 1996 Jan 15;235(1-2):231-7.

At sulfide concentrations higher than 10 microM, the cytochrome-c oxidase is blocked and electrons from sulfide are transferred to oxygen via an alternative terminal oxidase.
Mitochondrial respiration in the presence of malate (or succinate) and ADP but without sulfide could be completely inhibited by rotenone, antimycin, cyanide, and sulfide.
1(0,0,0,1) Details