| Name | alpha2 adrenoceptors (protein family or complex) |
|---|---|
| Synonyms | Alpha adrenoceptor; Alpha adrenoceptor; Alpha adrenergic receptor; Alpha adrenergic receptors; Alpha adrenoceptors; Alpha adrenoceptors; alpha1 Adrenoceptors; alpha1 Adrenoceptor… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19616571 | Alam M, Danysz W, Schmidt WJ, Dekundy A: Effects of and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats. Toxicol Appl Pharmacol. 2009 Oct 15;240(2):198-207. Epub 2009 Jul 17. The aim of this study was to elucidate whether neramexane nicotinic alpha9/alpha10 and 5-HT3 receptor antagonist), idazoxan (alpha2-adrenoceptor antagonist) or 2-methyl-6-(phenyl-ethyl)-pyrimidine (MPEP, metabotropic glutamate receptor 5 antagonist) prevents rotenone-induced parkinsonian-like behaviours and neurochemical changes in rats. |
31(0,1,1,1) | Details |
| 15764673 | Bailey SR, Mitra S, Flavahan S, Flavahan NA: Reactive species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries. Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H243-50. Epub 2005 Mar 11. Cold constricts cutaneous blood vessels by selectively increasing the activity of smooth muscle alpha2-adrenoceptors (alpha2-ARs). The inhibitor of mitochondrial complex I rotenone (10 micromol/l), the antioxidant (NAC; 20 mmol/l), or the cell-permeable mimic of superoxide dismutase MnTMPyP (50 micromol/l) did not affect vasoconstriction to alpha2-AR stimulation (UK-14304) at 37 degrees C but dramatically inhibited the response at 28 degrees C. |
1(0,0,0,1) | Details |