| Name | factor is |
|---|---|
| Synonyms | C3 inactivator; C3B/C4B inactivator; C3b inactivator; C3b INA; CFI; CFI protein; Complement component 3 inactivator; Complement component I… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3502252 | Griffith TM, Edwards DH, Henderson AH: Unstimulated release of endothelium derived relaxing factor is independent of mitochondrial generation. Cardiovasc Res. 1987 Aug;21(8):565-8. |
1(0,0,0,1) | Details |
| 3085949 | Griffith TM, Edwards DH, Newby AC, Lewis MJ, Henderson AH: Production of endothelium derived relaxant factor is dependent on oxidative phosphorylation and extracellular Cardiovasc Res. 1986 Jan;20(1):7-12. |
1(0,0,0,1) | Details |
| 11435296 | Vaux EC, Metzen E, Yeates KM, Ratcliffe PJ: Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood. 2001 Jul 15;98(2):296-302. Furthermore, concentrations of rotenone that maximally inhibited respiration did not affect HIF activation by hypoxia. |
1(0,0,0,1) | Details |
| 3653925 | Matthews N, Neale ML, Jackson SK, Stark JM: Tumour cell killing by tumour necrosis factor: inhibition by anaerobic conditions, free-radical scavengers and inhibitors of metabolism. Immunology. 1987 Sep;62(1):153-5. Previous work on the mechanism of tumour-cell killing by the macrophage product tumour necrosis factor (TNF) is consistent with a free radical-induced process. Suppression of metabolism by steroids effectively inhibited TNF cytolysis but the mitochondrial poison rotenone did not. |
1(0,0,0,1) | Details |
| 17848102 | Kim-Han JS, O'Malley KL: Cell stress induced by the parkinsonian mimetic, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation. Antioxid Redox Signal. 2007 Dec;9(12):2255-64. One such factor is (6-OHDA), which is widely used as a parkinsonian mimetic. Present findings show that 6-OHDA, but not peroxide, MPP+, or rotenone, leads to the rapid formation of high-molecular-weight species of protein disulfide isomerase-associated protein 3 (ERp57) in a dose- and time-dependent fashion. |
1(0,0,0,1) | Details |
| 6548538 | Hattori MA, Aquilano DR, Dufau ML: An early steroidogenic defect in hormone-induced Leydig cell desensitization. J Steroid Biochem. 1984 Sep;21(3):265-77. These results have demonstrated that a heat-labile inhibiting protein factor is present in mitochondria from normal Leydig cells and is markedly activated or increased by hCG treatment. |
1(0,0,0,1) | Details |