Protein Information

Name Par 4
Synonyms Coagulation factor II receptor like 3; PAR4; Par 4; F2RL3; Proteinase activated receptor 4; Proteinase activated receptor 4 precursor; Thrombin receptor like 3; coagulation factor II (thrombin) receptor like 3…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
10514095 Duan W, Zhang Z, Gash DM, Mattson MP: Participation of prostate apoptosis response-4 in degeneration of dopaminergic neurons in models of Parkinson's disease. Ann Neurol. 1999 Oct;46(4):587-97.

Exposure of cultured human dopaminergic neural cells to the complex I inhibitor rotenone, or to Fe2+, resulted in Par-4 induction, mitochondrial dysfunction, and subsequent apoptosis.
67(0,2,2,7) Details