| Name | ATF4 |
|---|---|
| Synonyms | ATF 4; CREB2; ATF4; Activating transcription factor 4; CREB 2; Cyclic AMP dependent transcription factor ATF4; Cyclic AMP response element binding protein 2; Cyclic AMP dependent transcription factor ATF 4… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17276738 | Fujita Y, Ito M, Nozawa Y, Yoneda M, Oshida Y, Tanaka M: CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations. Mitochondrion. 2007 Feb-Apr;7(1-2):80-8. Epub 2006 Dec 3. We found that mRNA and protein levels of ATF4, CHOP and ASNS were upregulated in 2SD and NARP3-1 cells as compared with parental cells. |
4(0,0,0,4) | Details |
| 19233273 | Silva JM, Wong A, Carelli V, Cortopassi GA: Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia. Neurobiol Dis. 2009 May;34(2):357-65. Epub 2009 Feb 20. The same doses of rotenone that reduced ATP production also induced dose-dependent increases in PERK and eIF2alpha phosphorylation as well as activated the ISR stress genes, ATF4 and CHOP. |
31(0,1,1,1) | Details |