| 17686240 |
Wang L, Cao XB, Wang JM, Qu RS, Xu L, Qiao X, Sun SG: [Proteolytic stress induced by environmental toxins in dopaminergic neurons: an experimental study]. Zhonghua Yi Xue Za Zhi. 2007 May 8;87(17):1190-4.
Compared with those in the control group, the trypsin-like, chymotrypsin-like, and PgH-like activities of proteasome were markedly decreased in the MPP (+) and rotenone groups (all P < 0.05) and slightly decreased in the 6-OHDA 100 micromol/L group (all P > 0.05), but after the exposure to 6-OHDA 200 micromol/L for 24 h, the activities of the three enzymes decreased rapidly, the activities of the three enzymes were 7.2 +/- 0.6, 79.6 +/- 2.7 and 4.2 +/- 0.5 FU/100 microg respectively (vs 13.9 +/- 1.8, 99.3 +/- 5.2, and 6.9 +/- 0.6 FU/100 microg respectively in the control group, all P < 0.01). |
6(0,0,1,1) |
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