Protein Information

Name glycine decarboxylase
Synonyms GCE; P protein; NKH; GCSP; GLDC; Glycine cleavage system P protein; Glycine decarboxylase; Glycine decarboxylase P protein…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
11299009 Bykova NV, Moller IM: Involvement of matrix NADP turnover in the oxidation of NAD-linked substrates by pea leaf mitochondria. Physiol Plant. 2001 Apr;111(4):448-456.


The involvement of the internal rotenone-insensitive NADPH dehydrogenase on the inner surface of the inner mitochondrial membrane [NDin (NADPH)] in the oxidation of strictly NAD+-linked substrates by pea (Pisum sativum L.) leaf mitochondria was measured.
0(0,0,0,0) Details
16667685 Pascal N, Dumas R, Douce R: Comparison of the Kinetic Behavior toward Pyridine Nucleotides of NAD-Linked Dehydrogenases from Plant Mitochondria. Plant Physiol. 1990 Sep;94(1):189-193.

In this article we compare the kinetic behavior toward pyridine nucleotides (NAD (+), NADH) of NAD (+)-malic enzyme, pyruvate dehydrogenase, isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, and glycine decarboxylase extracted from pea (Pisum sativum) leaf and potato (Solanum tuberosum) tuber mitochondria.
It is suggested that NAD (+)-linked malic enzyme, when fully activated, is able to raise the matricial NADH level up to the required concentration to fully engage the rotenone-resistant internal NADH-dehydrogenase, whose affinity for NADH is weaker than complex I.
1(0,0,0,1) Details
7389918 Moore AL, Dench JE, Jackson C, Hall DO: Glycine decarboxylase activity in plant tissues measured by a rapid assay technique. FEBS Lett. 1980 Jun 16;115(1):54-8.

1(0,0,0,1) Details
9256232 Igamberdiev AU, Bykova NV, Gardestrom P: Involvement of cyanide-resistant and rotenone-insensitive pathways of mitochondrial electron transport during oxidation of glycine in higher plants. FEBS Lett. 1997 Jul 28;412(2):265-9.

The involvement of different paths of electron transport in mitochondria during operation of glycine decarboxylase complex (GDC) was tested in different conditions, using aminoacetonitrile (AAN), the inhibitor of glycine oxidation in mitochondria, rotenone, the inhibitor of Complex I of mitochondrial electron transport, and inhibitors of cytochrome oxidase and alternative oxidase.
1(0,0,0,1) Details