| Name | albumin |
|---|---|
| Synonyms | ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 540045 | Livesey G, Williams KE: Hydrolysis of an exogenous 125I-labelled protein by rat yolk sacs. Biochem J. 1979 Dec 15;184(3):519-26. Progressively decreasing the rat of pinosome formation (either by progressively lowering the incubation temperature or by the use of increasing concentrations of the metabolic inhibitor rotenone) caused a corresponding decrease in the rate of degradation of albumin. |
82(1,1,1,2) | Details |
| 6426323 | DuBose TD Jr, Caflisch CR, Bidani A: Role of metabolic CO2 production in the generation of elevated renal cortical PCO2. Am J Physiol. 1984 May;246(5 Pt 2):F592-9. PCO2 was measured in vivo with PCO2 microelectrodes in early (EP) and late proximal (LP) tubules and stellate vessels (SV) during control conditions and after hyperoncotic albumin, aortic constriction, vanadate, rotenone, or 2,4-dinitrophenol (2,4-DNP) per renal artery, and carbonic anhydrase infusion. |
7(0,0,1,2) | Details |
| 11961005 | Morigi M, Macconi D, Zoja C, Donadelli R, Buelli S, Zanchi C, Ghilardi M, Remuzzi G: Protein overload-induced NF-kappaB activation in proximal tubular cells requires H (2) O (2) through a PKC-dependent pathway. J Am Soc Nephrol. 2002 May;13(5):1179-89. To identify the enzymatic sources responsible for the increased H (2) O (2) production, the effect of dyphenyleneiodonium, an inhibitor of the membrane (H) oxidase, was studied, as was the effect of rotenone, which blocks complex I of the mitochondrial respiratory chain. It has been previously shown that in porcine proximal tubular cells high concentrations of albumin activated NF-kappaB, which is responsible for the enhanced synthesis of the inflammatory chemokine RANTES. |
4(0,0,0,4) | Details |
| 3942135 | Shanley PF, Brezis M, Spokes K, Silva P, Epstein FH, Rosen S: Differential responsiveness of proximal tubule segments to metabolic inhibitors in the isolated perfused rat kidney. Am J Kidney Dis. 1986 Jan;7(1):76-83. Rat kidneys were perfused for 90 minutes with rotenone, antimycin, 2-deoxyglucose, or combinations of rotenone or antimycin with 2-deoxyglucose in oxygenated Krebs-albumin medium. |
6(0,0,1,1) | Details |
| 2382720 | Waldrop GL, Ettinger MJ: Effects of albumin and on kinetics of transport by fibroblasts. Am J Physiol. 1990 Aug;259(2 Pt 1):G212-8. |
4(0,0,0,4) | Details |
| 3004406 | Hopewell R, Martin-Sanz P, Martin A, Saxton J, Brindley DN: Regulation of the translocation of phosphatidate phosphohydrolase between the cytosol and the endoplasmic reticulum of rat liver. Biochem J. 1985 Dec 1;232(2):485-91. Effects of unsaturated fatty acids, nucleotides, albumin and chlorpromazine.. The phosphohydrolase that associated with the membranes in the presence of [14C] or 1mM- coincided on Percoll gradients with the peak of rotenone-insensitive -cytochrome c reductase, and in the former case with a peak of 14C. |
3(0,0,0,3) | Details |
| 11216526 | Marshall RC, Powers-Risius P, Reutter BW, Taylor SE, VanBrocklin HF, Huesman RH, Budinger TF: Kinetic analysis of 125I-iodorotenone as a deposited myocardial flow tracer: comparison with 99mTc-sestamibi. J Nucl Med. 2001 Feb;42(2):272-81. METHODS: The kinetics of these two flow tracers were evaluated in 25 isolated, erythrocyte- and albumin-perfused rabbit hearts over a flow range relevant to patients. |
2(0,0,0,2) | Details |
| 15534068 | Marshall RC, Powers-Risius P, Reutter BW, O'Neil JP, La Belle M, Huesman RH, VanBrocklin HF: Kinetic analysis of 18F-fluorodihydrorotenone as a deposited myocardial flow tracer: comparison to 201Tl. J Nucl Med. 2004 Nov;45(11):1950-9. METHODS: The kinetics of these flow tracers in 22 isolated, erythrocyte- and albumin-perfused rabbit hearts were evaluated over a flow range encountered in patients. |
2(0,0,0,2) | Details |
| 16572112 | Lin CL, Wang FS, Kuo YR, Huang YT, Huang HC, Sun YC, Kuo YH: Ras modulation of activates ERK-dependent fibronectin expression in diabetes-induced renal injuries. Kidney Int. 2006 May;69(9):1593-600. Transforming growth factor (TGF)-beta1, fibronectin expression, Ras, ERK, p38, and c-Jun activation of glomerular mesangial cells or urinary albumin secretion were assessed. Pretreatment with diphenyliodonium, not allopurinol or rotenone, reduced high- and AGE augmentation of synthesis and fibronection expression. |
2(0,0,0,2) | Details |
| 4170712 | Weinbach EC, Garbus J: Structural changes in mitochondria induced by uncoupling reagents. Biochem J. 1968 Feb;106(3):711-7. These effects, although opposite in direction to those obtained with albumin, are also presumed to indicate structural changes in the mitochondrial proteins and a disorganization of the protein-phospholipid complex. |
1(0,0,0,1) | Details |
| 5167173 | Cowger ML: Mechanism of toxicity on tissue culture cells: factors that affect toxicity, reversibility by albumin, and comparison with other respiratory poisons and surfactants. Biochem Med. 1971 Feb;5(1):1-16. |
1(0,0,0,1) | Details |
| 6817820 | Clouet P, Henninger C, Bezard J: [Modes of action of a shortening system for at the mitochondrial level of rat liver]. Biochimie. 1982 Oct;64(10):899-906. In this work, were studied the conditions of (cis-docosenoic, n-9) shortening by using Rat liver mitochondrial preparations which were incubated in vitro with [14-14C] (22:1), with inhibitors of the respiratory chain (rotenone, or not, with activators of either the shortening reaction (NAD+, or beta-oxidation cytochrome c) or not. Data showed that, with increasing amounts of albumin, which inhibits peroxysomal activity, increasing amounts of shorter fatty acids (20:1, 18:1, 16:1) were formed from |
1(0,0,0,1) | Details |
| 20227863 | He M, Siow RC, Sugden D, Gao L, Cheng X, Mann GE: Induction of HO-1 and redox signaling in endothelial cells by advanced glycation end products: A role for Nrf2 in vascular protection in diabetes. Nutr Metab Cardiovasc Dis. 2010 Mar 12. We have investigated the mechanisms by which AGE-modified bovine albumin (AGE-BSA) induces reactive species (ROS) generation, leading to nuclear factor-erythroid 2-related factor (Nrf2) dependent induction of the antioxidant genes heme oxygenase-1 (HO-1) and NADPH:quinone oxidoreductase 1 (NQO1) in bovine aortic endothelial cells. Inhibition of ROS production with the scavenger Tiron or inhibitors of flavoproteins (diphenylene iodonium) and oxidase (apocynin), but not eNOS (l-NAME) or mitochondria complex I (rotenone) abrogated HO-1 induction by AGE-BSA. |
1(0,0,0,1) | Details |