Protein Information

Name IkappaBalpha
Synonyms I kappa B alpha; Mad3; IKB alpha; IKBA; IKBalpha; IkappaBalpha; Inhibitor of kappa light chain gene enhancer in B cells alpha; MAD 3…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
16539850 Chen WH, Chen Y, Cui GH: Deguelin inhibits expression of IkappaBalpha protein in Raji and U937 cells. Acta Pharmacol Sin. 2006 Apr;27(4):485-90.

8(0,0,0,8) Details
17568818 Geeraerts B, Vanhoecke B, Vanden Berghe W, Philippe J, Offner F, Deforce D: Deguelin inhibits expression of IkappaBalpha protein and induces apoptosis of B-CLL cells in vitro. Leukemia. 2007 Aug;21(8):1610-8. Epub 2007 Jun 14.

3(0,0,0,3) Details
17015749 Nair AS, Shishodia S, Ahn KS, Kunnumakkara AB, Sethi G, Aggarwal BB: Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J Immunol. 2006 Oct 15;177(8):5612-22.

2(0,0,0,2) Details