| Name | butyrylcholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | EPN |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 4299018 | DuBois KP, Kinoshita FK, Frawley JP: Quantitative measurement of inhibition of aliesterases, acylamidase, and cholinesterase by EPN and Delnav. Toxicol Appl Pharmacol. 1968 Mar;12(2):273-84. |
81(1,1,1,1) | Details |
| 4741776 | Sato T, Moroi K: Comparative studies on the inhibition of liver amidases, aminopeptidase and serum cholinesterases by EPN. Toxicol Appl Pharmacol. 1973 Aug;25(4):553-9. |
31(0,1,1,1) | Details |
| 14474998 | MOELLER HC, RIDER JA: Plasma and red blood cell cholinesterase activity as indications of the threshold of incipient toxicity of ethyl-p-nitrophenyl thionobenzenephosphonate (EPN) and malathion in human beings. Toxicol Appl Pharmacol. 1962 Jan;4:123-30. |
6(0,0,1,1) | Details |
| 5531408 | Sato T, Yoshida S, Ogura Y, Moroi K: [Effect of ethyl-p-nitrophenyl phenylphosphonothiate (EPN) on tryptophan pyrrolase activity in relation to miosis and change in serum cholinesterase activities] Nippon Yakurigaku Zasshi. 1970 Jul 20;66(4):387-93. |
6(0,0,1,1) | Details |
| 13114894 | DISTEFANO V, HURWITZ L: The development of an anticholinesterase substance in highly purified EPN. Arch Biochem Biophys. 1953 Nov;47(1):228. |
6(0,0,1,1) | Details |
| 3775801 | Yasoshima M, Masuda Y: Effect of carbon disulfide on the anticholinesterase action of several organophosphorus insecticides in mice. Toxicol Lett. 1986 Sep;32(3):179-84. |
4(0,0,0,4) | Details |
| 6525997 | Awad OM: Molecular mechanism for the inhibition of acetylcholinesterase enzyme by organophosphorothionates. Enzyme. 1984;32(4):193-200. The different mechanisms, whereby EPN and malathion inhibit the action of cholinesterase on are described. |
2(0,0,0,2) | Details |
| 2719724 | Pla A, Johnson MK: Degradation by rat tissues in vitro of organophosphorus esters which inhibit cholinesterase. Biochem Pharmacol. 1989 May 1;38(9):1527-33. |
2(0,0,0,2) | Details |
| 13059622 | LEACH PH: Organic poisoning in general practice; parathion, TEPP, HEPT, EPN and others. Calif Med. 1953 Jun;78(6):491-5. The organic radical has the specific effect of inactivating cholinesterase in the body. |
2(0,0,0,2) | Details |
| 17335779 | Schallreuter KU, Gibbons NC, Elwary SM, Parkin SM, Wood JM: -activated butyrylcholinesterase in human skin protects acetylcholinesterase against suicide inhibition by organophosphates. Biochem Biophys Res Commun. 2007 Apr 20;355(4):1069-74. Epub 2007 Feb 23. Moreover, we confirmed the faster hydrolysis by -activated BuchE using the organophosphate O-ethyl-O--phenylphosphonothioate (EPN). |
2(0,0,0,2) | Details |
| 72768 | El-Sebae AH, Soliman SA, Elamayem MA, Ahmed NS: Neurotoxicity of organophosphorus insecticides Leptophos and EPN. J Environ Sci Health B. 1977;12(4):269-87. The five tested organophosphorus insecticides were compared for their ability to inhibit cholinesterase, neurotoxic esterases and monoamine oxidase. |
2(0,0,0,2) | Details |
| 6169754 | El-Sebae AH, Soliman SA, Ahmed NS, Curley A: Biochemical interaction of six OP delayed neurotoxicants with several neurotargets. J Environ Sci Health B. 1981;16(4):465-74. The six compounds and their oxons were screened for their in-vitro inhibition to monamine oxidase (MAO), acetyl cholinesterase (AChE) and neurotoxic esterase (NTE) in the brain of either mouse, lamb or chicken. |
1(0,0,0,1) | Details |
| 10421485 | Satoh T, Suzuki S, Kawai N, Nakamura T, Hosokawa M: Toxicological significance in the cleavage of esterase-beta-glucuronidase complex in liver microsomes by organophosphorus compounds. Chem Biol Interact. 1999 May 14;119-120:471-8. From these in vivo and in vitro data, it is concluded that increase of the plasma beta-G level after OP administration is much more sensitive biomarker than cholinesterase inhibition to acute intoxication of OPs and carbamates. |
1(0,0,0,1) | Details |
| 6205472 | Hoffman DJ, Sileo L, Murray HC: Subchronic organophosphorus ester-induced delayed neurotoxicity in mallards. Toxicol Appl Pharmacol. 1984 Aug;75(1):128-36. Brain acetylcholinesterase, plasma cholinesterase, and plasma alkaline phosphatase were significantly inhibited as well. |
1(0,0,0,1) | Details |
| 14496523 | SALVINI M, TOMINZ L: [Experimental prevention of the anticholinesterase action of organophosphates. Med Lav. 1961 Nov;52:676-83. Effect of -2- sulfomethylate (RP-7676) per os, in chronic oral poisoning with EPN and malathion.] |
1(0,0,0,1) | Details |
| 2339420 | Silveira CL, Eldefrawi AT, Eldefrawi ME: Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases. Toxicol Appl Pharmacol. 1990 May;103(3):474-81. There was poor correlation between the potencies of the OPs in reversibly inhibiting [3H] CD binding, and their anticholinesterase activities and toxicities. |
1(0,0,0,1) | Details |
| 6685263 | Abou-Donia MB, Graham DG, Makkawy HA, Abdo KM: Effect of subchronic dermal application of O-ethyl O- phenylphosphonothioate on producing delayed neurotoxicity in hens. Neurotoxicology. 1983 Summer;4(2):247-60. EPN and TOCP treatments had a more profound effect on the activity of plasma butyrylcholinesterase than that of brain acetylcholinesterase (AchE). by contrast O,O,-diethyl O- phosphorothioate (parathion) was more inhibitory to brain AChE. |
1(0,0,0,1) | Details |